TRANSCRIPTOMIC AND GENOMIC SEARCH OF ENDOMETRIAL RECEPTIVITY MARKERS IN WOMEN WITH RECURRENT IMPLANTATION FAILURE
نویسندگان
چکیده
منابع مشابه
Endometrial beta3 Integrin profile reflects endometrial receptivity defects in women with unexplained recurrent pregnancy loss
BACKGROUND The pathophysiology of recurrent pregnancy loss (RPL) is still unknown in 50% of the cases. Herein we measure the expression of beta3 integrin subunit, a well-known implantation marker, in women with or without RPL and correlate it with the histological dating of the endometrial tissue. METHODS LH-timed endometrial biopsies were obtained from cases (RPL; n = 21, age 33.9+/-4.7) and...
متن کاملBiomarkers Related to Endometrial Receptivity and Implantation
Implantation is a process requiring the delicate interaction between the embryo and a receptive endometrium. This intricate interaction requires a harmonized dialogue between embryonic and maternal tissues. [Aghajanova et al., 2008; Simon et al., 2000] The three stages of implantation are: apposition, adhesion, and invasion. Apposition describes trophoblast cells adhering to the receptive endom...
متن کاملDisturbed endometrial NF-κB expression in women with recurrent implantation failure.
OBJECTIVE This study was planned to investigate whether expression levels of endometrial NF-κB1 and NFκB p65 changes in women with recurrent implantation failure (RIF). PATIENTS AND METHODS The study group consists of 30 RIF patients having at least three previous failed IVF cycles. The control group comprises of 30 patients having one or no previous failed attempt. Endometrial samples were o...
متن کاملI-24: Recurrent Implantation Failure
Recurrent implantation failure (RIF) has many definitions, but usually authors consider RIF, the failure to achieve a pregnancy fallowing 2-6 IVF cycles in which more than 10 high grade embryos were transferred to the uterus. There are a lot of causes for RIF but two main causes of that are related to embryo and endometrium. Chromosomal abnormalities, zona hardening and problems in culture medi...
متن کاملendometrial receptivity to implantation in humans: biochemical and molecular aspects
the success rate of several advanced basic and clinical techniques in the field of mammalian biotechnology, including cloning, pre-implantation genetic diagnosis, and assisted reproductive techniques (art) depends mainly on the success rate of pregnancy following in vitro fertilization-embryo transfer (ivfet). the techniques used in art have advanced considerably since the first in vitro fertil...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2020
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2020.09.047